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Glossary entry

German term or phrase:

Chinaalkaloide

English translation:

cinchona alkaloids

Added to glossary by Dr. Johanna Schmitt
Jan 17, 2014 15:49
10 yrs ago
German term

Chinaalkaloiden

German to English Science Chemistry; Chem Sci/Eng
Google hits give "China alkaloids" as a translation, but I have my doubts.
Anyone?

I'd be more inclined to think along the lines of 'cinchona alkaloids'...but I am not a chemist :):)

Thanks for your input!
Proposed translations (English)
3 +3 cinchona alkaloids
4 -1 Quinine alkaloids
References
China-Alkaloide
To add to Marga's reference
Change log

Jan 20, 2014 08:23: Dr. Johanna Schmitt Created KOG entry

Discussion

Lirka (asker) Jan 19, 2014:
@rainerc 1905 :):)
rainerc (X) Jan 17, 2014:
@ lirka: classification Yorkshireman has just opened up a can of worms, so to speak :-) The chemistry of natural products and in particular that of the alkaloids is rather complex. Initially they were classified on the basis of their plant origins (taxonomic classif.). Once IUPAC nomenclature was developed, the chemical structure became the basis. I need some more info on the kind and date of the text in order to come up with the best translation. "Chinaalkaloide" sounds very much like early 20th century in which case the plant origin (cinchona) applies.
Coqueiro Jan 17, 2014:
Chinolin/Quinoline maybe?

Keine Ergebnisse für "China alkaloids" -china -alibaba gefunden ;-)
Lirka (asker) Jan 17, 2014:
Context It appears in a title "Dibromadditionsprodukte der Chinaalkaloide"

Proposed translations

+3
35 mins
Selected

cinchona alkaloids

Chinaalkaloide sind die Alkaloide der Chinarinde:

http://ptaforum.pharmazeutische-zeitung.de/index.php?id=43

http://www.dict.cc/?s=chinarinde

http://en.wikipedia.org/wiki/Cinchona#Cinchona_alkaloids

--------------------------------------------------
Note added at 40 mins (2014-01-17 16:29:57 GMT)
--------------------------------------------------

Yes, you were right :-) !
Note from asker:
Thanks a lot, so it seems I was on the right track with this...
Peer comment(s):
agree Coqueiro
8 mins
Vielen Dank, Coqueiro!
agree rainerc (X) : see my discussion entry. // The additional references confirm that the taxonomic classification is best in this case.
38 mins
Vielen Dank, rainerc!
agree Marga Shaw : See Hunnius "Pharmazeutisches Wörterbuch" and Römpp "Chemie Lexikon"
8 hrs
Vielen Dank, Marga!
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thanks so much!"
-1
1 hr

Quinine alkaloids

Has nothing to do with China, the name is a corruption of Quina.

Alkaloids extracted from the bark of the South American Cinchona or Quina tree. In 1860, the British smuggled plants and seeds from South America and cultivated them in Ceylon (Sri Lanka) and various tea-growing areas of the Raj (India), the best known being Darjeeling. This became invaluable for combating malaria in the British colonies.

Quinine also known as Jesuit's Bark or Peruvian Bark and, as Dr J. already mentioned in her answer, the alkaloids extracted or synthesised are also collectively known as cinchona alkaloids.
Peer comment(s):
disagree rainerc (X) : see discussion. // The quinine alkaloids are one of many in the cinchona bark.
1 hr
neutral Cilian O'Tuama : cinchona or quina, no need for capitals
8 hrs
neutral Marga Shaw : please see my reference comment
15 hrs
Something went wrong...

Reference comments

9 hrs
Reference:

China-Alkaloide

China-Alkaloide: Cinchona-Alkaloide; über 30 in Cinchona-Arten vorkommende Chinolinalkaloide, z.B. Chinin, Chinidin, Cinchonidin, Cinchonin. Biogenese erfolgt wie bei den Indolalkaloiden von Tryptophan ausgehend, wobei es nach Einbau eines Monoterpenbausteins und anschließender Umlagerung zur Sprengung des Indolringsystems und neuerlichem Ringschluss zur Ausbildung des Chinolensystems kommt. Chinin und Chinidin sowie Cinchonin und Cinchonidin sind Diastereomere, die sich durch eine konfigurative Umkehr am C-Atom 8 und 9 unterscheiden. Nachweis: mit der Thalleiochin-Reaktion.
(Hunnius "Pharmazeutisches Wörterbuch", 8. Auflage, de Gruyter)

China-Alkaloide
Therapeutisch wichtige Alkaloide aus der Chinarinde (Cortex Chinae), die aus der Rinde verschiedener Cinchona-Arten (Rubiaceae) gewonnen wird, Mindestgehalt an Alkaloiden 6,5 %. Zu den C. gehören die Chinolin-Derivate Chinin (ca. 80 % des Gesamtgehaltes an Alkaloiden), Chinidin, Cinchonin und Cinchonidin, außerdem sind Indol-Alkaloide enthalten. Bei den Chinolin-Alkaloiden ist der Chinolin-Ring über eine C-Brücke mit dem tricyclischen Chinuclidin-Ring (1-Azabicyclo[2.2.2]octan), der in 3-Stellung eine Vinylgruppe trägt, verbnden. Die als Nebenalkaloide vorkommenden Epibasen besitzen eine andere Konfiguaration an C-9 als die Normalbasen.
E cinchona alkaloids
(Römpp "Chemie Lexikon", Thieme, 9. erweiterte und bearbeitete Auflage)
Peer comments on this reference comment:
agree Coqueiro : Toll! // Fachbücher sind oft sehr gute Quellen, ausführlich aus ihnen zu zitieren erfordert jedoch sehr viel mehr Mühe als das übliche Copy & Paste. Nicht oft zu sehen.
6 hrs
Thank you, Coqueiro! The ref. material was staring at me yesterday evening.
Something went wrong...
21 hrs
Reference:

To add to Marga's reference

http://www.medizinalpflanzen.de/systematik/6_droge/chinae-c....

"Chinarinde - Englisch: Cinchona bark, Jesuit's bark, Peruvian bark, Red bark, Red Cinchona bark."
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