Glossary entry (derived from question below)
English term or phrase:
media challenge studies
Spanish translation:
estudios de provocación con medios
Added to glossary by
sebaspedlp
Jul 25, 2019 16:15
4 yrs ago
14 viewers *
English term
media challenge studies
Homework / test
English to Spanish
Medical
Medical: Pharmaceuticals
The utility of human challenge studies in vaccine development: lessons learned from cholera.
We routinely monitors the integrity of syringes with Container Closure Integrity testing during media challenge studies, filling in-process checks of syringes and by product sterility testing.
Human challenge studies may also provide valuable information.
Good morning, we are working on the translation or a report of several summaries for our teacher at university, we have to translate several articles (the summary) with different sentences with words in common.
We are now with the challenge studies phrase use with different words... when faced with media challenge studies we do not know how to translate it....
we thought about: estudios de exposición a distintos medios / estudios de desafio a distintos medios.... we really didnt find anything to help us. Thanks for your help.
We routinely monitors the integrity of syringes with Container Closure Integrity testing during media challenge studies, filling in-process checks of syringes and by product sterility testing.
Human challenge studies may also provide valuable information.
Good morning, we are working on the translation or a report of several summaries for our teacher at university, we have to translate several articles (the summary) with different sentences with words in common.
We are now with the challenge studies phrase use with different words... when faced with media challenge studies we do not know how to translate it....
we thought about: estudios de exposición a distintos medios / estudios de desafio a distintos medios.... we really didnt find anything to help us. Thanks for your help.
Proposed translations
(Spanish)
3 | estudios de provocación con medios | María Patricia Arce |
2 | estudios de reto sobre caldos de cultivo | JohnMcDove |
Proposed translations
6 hrs
Selected
estudios de provocación con medios
Por "media" entiendo como John que se trata de los medios de cultivo para el crecimiento de microorganismos.
Ref:
In 1796 Edward Jenner, injected a young boy James Phipps with fluid from a cowpox blister. He then tested this (conducted a human challenge study) by "variolating" him - the protective treatment then available. Click here for a longer description.
Human Infection Challenge Studies. http://www.reviewingresearch.com/human-challenge-studies/
En estudios de provocación experimental en voluntarios, la infección clínica inicial por V. cholerae O139 confirió protección significativa contra la diarrea, al provocar de nuevo al sujeto con el V. cholerae O139. http://www1.paho.org/hq/dmdocuments/2010/9275315817.pdf
Se incluirá documentación acerca de ensayos de provocación que demuestren la protección inducida por la vacuna. Si la vacuna está destinada a la protección del recién nacido se presentarán ensayos realizados en animales gestantes, que evalúen la respuesta inmunológica del feto y el nivel de protección frente al estudio de provocación.
http://www.anmat.gov.ar/webanmat/Legislacion/Medicamentos/Di...
Investigators and ethics committees should recognise that contamination of biological material for ***challenge studies*** can occur at different stages in its preparation: for example, during the original isolation of the challenge agent (e.g. nasopharyngeal secretions could be contaminated with retroviruses); during its amplification (e.g. through the use of ***growth media*** or primary cell culture that may contain prions, oncogenic viruses etc); through cross-contamination in the production facility; and during its subsequent aliquoting and storage. […] Without formal guidance equivalent to Good Laboratory Practice (GLP), GCP and Good Manufacturing Practice GMP academic researchers were previously faced with a choice of manufacturing challenge agents locally using the best available local resources, or entering into a relationship to obtain a commercially-prepared challenge agent that is prepared to the standards required for vaccine manufacture. Key elements for quality control include: [´…]well-characterised and documented growth and maintenance media
https://acmedsci.ac.uk/file-download/34726-1127728424.pdf
Ref:
In 1796 Edward Jenner, injected a young boy James Phipps with fluid from a cowpox blister. He then tested this (conducted a human challenge study) by "variolating" him - the protective treatment then available. Click here for a longer description.
Human Infection Challenge Studies. http://www.reviewingresearch.com/human-challenge-studies/
En estudios de provocación experimental en voluntarios, la infección clínica inicial por V. cholerae O139 confirió protección significativa contra la diarrea, al provocar de nuevo al sujeto con el V. cholerae O139. http://www1.paho.org/hq/dmdocuments/2010/9275315817.pdf
Se incluirá documentación acerca de ensayos de provocación que demuestren la protección inducida por la vacuna. Si la vacuna está destinada a la protección del recién nacido se presentarán ensayos realizados en animales gestantes, que evalúen la respuesta inmunológica del feto y el nivel de protección frente al estudio de provocación.
http://www.anmat.gov.ar/webanmat/Legislacion/Medicamentos/Di...
Investigators and ethics committees should recognise that contamination of biological material for ***challenge studies*** can occur at different stages in its preparation: for example, during the original isolation of the challenge agent (e.g. nasopharyngeal secretions could be contaminated with retroviruses); during its amplification (e.g. through the use of ***growth media*** or primary cell culture that may contain prions, oncogenic viruses etc); through cross-contamination in the production facility; and during its subsequent aliquoting and storage. […] Without formal guidance equivalent to Good Laboratory Practice (GLP), GCP and Good Manufacturing Practice GMP academic researchers were previously faced with a choice of manufacturing challenge agents locally using the best available local resources, or entering into a relationship to obtain a commercially-prepared challenge agent that is prepared to the standards required for vaccine manufacture. Key elements for quality control include: [´…]well-characterised and documented growth and maintenance media
https://acmedsci.ac.uk/file-download/34726-1127728424.pdf
4 KudoZ points awarded for this answer.
Comment: "Muchas gracias "
8 mins
estudios de reto sobre caldos de cultivo
"Media" me parece que se refiere a "medios" como "ambientes" o "caldos de cultivo".
Doy un nivel bajo de seguridad, porque no estoy muy seguro de si hay alguna terminología al uso.
Del concepto creo que sí estoy más seguro.
Saludos cordiales.
Doy un nivel bajo de seguridad, porque no estoy muy seguro de si hay alguna terminología al uso.
Del concepto creo que sí estoy más seguro.
Saludos cordiales.
Note from asker:
¡Muchas gracias! Saludos |
Discussion
Por ejemplo,
Estudios de estabilidad (Challenge test)
http://ainialab.ainia.es/microbiologia/