This site uses cookies. Some of these cookies are essential to the operation of the site, while others help to improve your experience by providing insights into how the site is being used. For more information, please see the ProZ.com privacy policy.
Cookie settings
just debts
"it"
Feb 9, 2010 13:58
14 yrs ago
English term

gene silencing

GBK English to Indonesian Science Biology (-tech,-chem,micro-)
Definition from MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.
Example sentences:
Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. (biotech-info.net)
The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? (The Thomson Corporation)
In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. (ScienceDaily LLC)
Proposed translations (Indonesian)
5 pembungkaman gen
4 +1 Peredaman gen
Change log

Feb 9, 2010 13:00: changed "Kudoz queue" from "In queue" to "Public"

Feb 9, 2010 13:58: changed "Stage" from "Preparation" to "Submission"

Feb 12, 2010 15:04: changed "Stage" from "Submission" to "Selection"

Proposed translations

5 days

pembungkaman gen

Pembungkaman gen disebut juga dengan peredaman gen.
Definition from MedicineNet, Inc.:
Pembungkaman gen ialah mekanisme ketika sel-sel menutup sebagian besar DNA khromosom.
Example sentences:
Publikasi tersebut menunjukkan teknik pembungkaman gen pada tumbuhan dalam mekanisme pertahanan terhadap virus, dan jelas menggambarkan penelitian pembungkaman gen pada tumbuhan selangkah lebih dahulu dibandingkan penelitian pembungkaman gen pada hewan dengan model pada cacing C. elegans yang digunakan oleh Fire dan Mello beserta kolega-koleganya. (Kamus Ilmiah)
Semakin banyak jumlah salinan gen yang disisipkan maka ekspresi gen kurang stabil akibat dari adanya pembungkaman gen dan proses penyusunan kembali (rearrangement) semakin tinggi yang mengakibatkan ekspresi gen kurang stabil (Dai et al. 2001). (ANEKAPLANTASIA.cybermediaclip)
Integrasi dan ekspresi gen masih belum jelas dimengerti. Cao et al. (2004) menyarankan penggunaan promoter yang berbeda untuk masing-masing kaset ekspresi, untuk menghindari terjadinya pembungkaman gen pada tahap transkripsi (transcriptional silencing). (Anak Belitang)
Something went wrong...
+1
77 days

Peredaman gen

Mempertegas penjelasan dari pak Wiyanto, hanya urutanya saja yang berbeda padanan kata 'Gene silencing', 'pembungkaman gen', dan 'pemadaman gen' beralih ke peredaman gen. Menurut Wikipedia, istilah dalam bahasa Indonesia ini dipilih karena paling mendekati makna istilah asli dan makna teknisnya
Definition from Wikipedia:
Sebagai padanan gene silencing, mengacu pada sejumlah metode yang dipakai dalam biologi molekular untuk menghalangi/meredam ekspresi gen memanipulasi bahan genetik secara terkendali. Dengan demikian, penggunaan mutagen seperti sinar radioaktif atau penggunaan bahan kimia per se tidak termasuk di dalamnya. Peredaman ekspresi gen dapat dilakukan pada tingkat DNA maupun RNA (lihat ekspresi genetik).
Example sentences:
Tahap-tahap penting berikutnya adalah serangkaian penemuan enzim restriksi (pemotong) DNA, regulasi (pengaturan ekspresi) DNA (diawali dari penemuan operon laktosa pada prokariota ), perakitan teknik PCR , transfprmasi genetik , teknik peredaman gen (termasuk interferensi RNA), dan teknik mutasi terarah (seperti Tilling) (Warta Gunadarma)
Peer comment(s):
agree Amin Masruri
587 days
Something went wrong...
Close search
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search