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founder mutation

Hebrew translation: מוטציית אב קדמון

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:founder mutation
Hebrew translation:מוטציית אב קדמון
Entered by: Tzviya Levin Rifkind

13:39 Apr 3, 2012
English to Hebrew translations [PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: founder mutation
In genetics, a founder mutation is a mutation that appears in the DNA of one or more individuals who are founders of a distinct population. Founder mutations initiate with changes that occur in the DNA and can get passed down to other generations.

המונח משמש בטקסט שלי להתייחס למוטציות ב
BRCA1/2
בסרטן השחלות

מצאתי כמה אזכורים ל"מוטציית מייסד" אבל קצת קשה לי עם זה יכול להיות שבעברית פשוט לא משתמשים במונח ואומרים מוטציות העוברות בתורשה או מוטציות מולדות?
Odded Leon
Israel
Local time: 19:05
מוטציית אב קדמון
Explanation:
מצלצל טוב יותר מאשר מייסד.
(מייסד = מישהו שפעל והקים דבר מה [וזה פחות מתאים כאן כי נושא הגן לא עשה שום דבר כדי לייסד שושלת של גן פגום]; אב קדמון = הראשון בשושלת).
Selected response from:

Tzviya Levin Rifkind
Israel
Local time: 19:05
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
5 +1מוטציית אב קדמון
Tzviya Levin Rifkind
5אב קדמון / מייסד
Eytan Rubinstien MD
3מוטציית מייסד
Gad Kohenov


Discussion entries: 2





  

Answers


6 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
מוטציית מייסד


Explanation:
מוטציית מייסד
ובסוגריים לכתוב את האנגלית. כנראה שאין עדיין טוב יותר

Gad Kohenov
Israel
Local time: 19:05
Native speaker of: Native in FrenchFrench, Native in HebrewHebrew
PRO pts in category: 8
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18 mins   confidence: Answerer confidence 5/5 peer agreement (net): +1
מוטציית אב קדמון


Explanation:
מצלצל טוב יותר מאשר מייסד.
(מייסד = מישהו שפעל והקים דבר מה [וזה פחות מתאים כאן כי נושא הגן לא עשה שום דבר כדי לייסד שושלת של גן פגום]; אב קדמון = הראשון בשושלת).


    Reference: http://www.gertnerinst.org.il/epidemiology/cancer/cancer_res...
Tzviya Levin Rifkind
Israel
Local time: 19:05
Specializes in field
Native speaker of: Native in HebrewHebrew
PRO pts in category: 4
1 corroborated select project
in this pair and field What is ProZ.com Project History(SM)?

Peer comments on this answer (and responses from the answerer)
agree  Aya Deutsch
55 mins
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3 hrs   confidence: Answerer confidence 5/5
אב קדמון / מייסד


Explanation:
some medical / biological texts distinguish between:
ancestral mutations
אב קדמון
and
founder mutations
מייסד

it may be necessary to make that distinction in your text too.

eytan

Eytan Rubinstien MD
Local time: 12:05
Specializes in field
Native speaker of: Native in HebrewHebrew, Native in EnglishEnglish
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