English to Italian Medical Medical: Pharmaceuticals Farmaco antidiabetico

Day 1

No food or insulin, only water can be given.
8 am: take basal HbA1c, paired Fasting glucose and C peptide.
Then, give breakfast, bolus insulin and the first dose of glibenclamide 0.1 mg/kg.
Continue measuring glucose before meals and before bed daily.
Administer bolus insulin with meals as required.
Give evening glibenclamide dose (0.1 mg/kg) unless capillary blood-glucose < 7 mmol/L. Give basal and/or bolus insulin as usual in the evening.


Day 2

Omit basal insulin and ** remain off this ** for the period of the transfer process.
If on insulin pump, reduce basal rate of insulin pump by 50% and reduce further in accordance with capillary blood-glucose measurements.
Throughout transfer period, administer bolus insulin or insulin pump boluses with meals as required to maintain reasonable glycemic control.