https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377267/
Artificial antigen-presenting cells (aAPCs) have recently gained a lot of attention. They efficiently activate T cells and serve as powerful replacements for dendritic cells in cancer immunotherapy. Focusing on a specific class of polymer-based aAPCs, so-called synthetic dendritic cells (sDCs), we have investigated the importance of multivalent binding on T-cell activation.
Two polymers of different average lengths (P1′ = 175 nm and P2′ = 350 nm; azide/methoxy = 1:100) were synthesized using this strategy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356674/
We determined the frequency of tetramer-binding cells from the periphery of cohorts of Aire+/+ and Aire−/− mice at 10–20 wk of age. There was a clear increase in the frequency of the P2-I-Ab–specific T-cell population in Aire−/−
mice...

http://molbiol.ru/forums/lofiversion/index.php/t405762.html
Вопрос - коллеги, не знает ли кто, существует ли возможность провести с нашими CD8 такой "скрининг" по этой группе антигенов (СТ) с помощью тетрамеров как "сервис" какой-то из компаний: это получится, вероятно, не дороже, чем заказывать тетрамеры на всю как минимум "узнаваемую сотню" - и т.к