English to Russian Science Biology (-tech,-chem,micro-)

he antigen-binding constructs exhibit anti-tumor activities in vitro, such as (i) the ability to inhibit cancer cell growth both in the presence or absence of stimulation by epidermal growth factor or heregulin, (ii) the ability to be internalized in cancer cells and (iii) the ability to mediate antibody-directed effector cell killing (ADCC). These in vitro activities are observed both with """naked antigen-binding constructs (i.e. unconjugated to drug or toxin)"", and with the antigen-binding constructs conjugated to maytansine, and at varying levels of HER2 expression (1+, 2+ and 3+).

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