Glossary entry (derived from question below)
Persian (Farsi) term or phrase:
دارد از دست می رود
English translation:
there is no hope for him.
Persian (Farsi) term
از دست رفتن
این بخشی از داستان است
Dec 28, 2014 16:54: Ali Fazel changed "Edited KOG entry" from "<a href="/profile/621986">Ali Fazel's</a> old entry - "از دست رفتن"" to ""They said he lost his mind & there is no hope for him""
Proposed translations
Iran
Present your smile to everyone
Native in: Persian (Farsi) 
Works in: English to Persian (Farsi)
They said he lost his mind & there is no hope for him
United States
Quality Is the Best Business Plan!
Native in: Persian (Farsi)
Works in: Persian (Farsi) to English, English to Persian (Farsi)
perish
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Note added at 39 mins (2014-12-27 07:01:56 GMT)
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Also:
one should cut down all expectations from him!
there is no hope for him to become a normal man again!
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Mohammad Reza Sabeti Zadeh
: Perish here does not mean to die, if you refer to the dictionary meaning of "perish", you face to this meaning: "to die, especially in a terrible or sudden way"
19 mins
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look at discussion, please!
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Iran
+15 Years of Professional Experience!
Native in: Persian (Farsi) (Variant: Iranian (standard))
Works in: English to Persian (Farsi), English to Dari, Persian (Farsi) to English
and is bound to be wasted/consumed/spent
The words used here are a bit archaic and mostly used in Bible text.
However, if you want a more-easy-to-understand expression, just go for things like:
and is dying/ is bound to die/pass away.
United Kingdom
English- Dari , English Farsi
Native in: Dari
Works in: Dari to Spanish, Persian (Farsi) to Spanish, Dari to English, and 9 more.
lacking in serviceability
he id dying
Iran
Currently NOT accepting new jobs
Native in: English (Variants: US, UK) , Persian (Farsi)
Works in: English to Persian (Farsi), Persian (Farsi) to English, English, and 13 more.
they said he's losing it.
2. To become deranged or mentally disturbed.
http://www.thefreedictionary.com/losing it
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Note added at 7 hrs (2014-12-27 13:57:56 GMT)
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فکر می کنم «دارد از دست می رود» به معنای مردن و ... نیست. در اینجا به معنای دیوانه شدن و به حالت نرمال برنگشتن است.
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Masoud Fahimkhah
4 hrs
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Thanks!
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sepideh javdani
9 hrs
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Thank you!
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Edward Plaisance Jr
: this captures it, I think...it doesn't mean he is dying soon, but rather his mind is going and will never be the same again
9 hrs
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Thanks Edward! Yes, that's what I said in the note I added later
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Mahmoud Reazi
: nice work!
23 hrs
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Thanks!
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Discussion
to cut down all expectations
there is no hope for him to become a normal man again
My explanatio:
First: از دست رفتن means مردن هلاک شدن بی اختیار شدن according to
http://www.vajehyab.com/moein/از دست رفتن
Second: according to Bateni's Dictionary
Perish means 1 هلاک شدن، تلف شدن، جان خود را از دست دادن
2 از بین رفتن ، نابود شدن
3خراب شدن، فاسد شدن
4پوسیدن
I suppose you can use "perish" in this part of its meaning از بین رفتن ، نابود شدن
َMy other reason to use "perish" is its literary sense.
http://www.thefreedictionary.com/perish
از دست رفتن here does not mean die or pass from existence. What do you think?