Glossary entry (derived from question below)
German term or phrase:
kausal wirkende Substanz
English translation:
causal treatment/therapy
German term
United States
GERMAN-ENGLISH PHARMA/MEDICAL TRANSLATOR
Native in: German 
, English
Works in: German to English
kausal wirkende Substanz
Der Einsatz von Botulinumtexin A (BTX-A) stellt eine innovative und nahezu ***kausal ansetzende Therapie*** mit lang-anhaltendem Effekt dar, der zu einer zufriedenstellenden Rehabilitation des Patienten führen kann.
Further down:
Bezugnehmend auf die integrierte Triggerpunkt-Hypothese erscheint Botulinumtoxin A (BTX-A) als eine ***nahezu kausal wirkende Substanz***.
And then in the summary:
BTX-A stellt eine mögliche wirkungsvolle therapeutische Strategie bei chronifizierten und therapie-refraktärem MPS [translator: myofascial pain syndrome] dar. Basierend auf dem derzeit favorisierten pathophysiologischen Modell erscheint BTX-A als ****nahezu kausal wirkende Substanz***.
***
Despite all the undergradute and graduate education that I did NOT snooze through, I cannot figure out what "kausal wirkend" means in this context.
Thanks for helping!!!
| 4 | causal treatment/therapy |
Harald Moelzer (medical-translator)
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| 4 | substance with a direct therapeutic effect |
Lirka
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| 3 +1 | drug/(substance/medication) treating the underlying cause |
uyuni
|
Nov 6, 2012 09:12: Coqueiro changed "Language pair" from "English to German" to "German to English"
Nov 6, 2012 13:24: Cilian O'Tuama changed "Level" from "Non-PRO" to "PRO"
Nov 11, 2012 06:33: Harald Moelzer (medical-translator) Created KOG entry
Nov 30, 2012 15:59: Harald Moelzer (medical-translator) changed "Field (specific)" from "Medical (general)" to "Medical: Pharmaceuticals"
PRO (3): BrigitteHilgner, Coqueiro, Cilian O'Tuama
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Proposed translations
Germany
Harald Moelzer (medical-translator) 
medical-translator ...the right words!
Native in: German 
Works in: English to German, German to English, French to German, and 1 more.
causal treatment/therapy
...would be a straight forward translation, e.g. see here:
"Stratification and weighting via the propensity score in estimation of causal treatment effects"
http://onlinelibrary.wiley.com/doi/10.1002/sim.1903/abstract
http://www.faqs.org/patents/app/20120269762
...or even """causally targeted therapy/treatment""" as used here:
"...The immense physical, psychological, and economic cost of diabetic neuropathy underscore the need for causally targeted therapies..."
http://www.ibbr.umd.edu/publications/diabetic-neuropathy-mec...
substance with a direct therapeutic effect
| Thank you for much for helping. |
drug/(substance/medication) treating the underlying cause
http://pubs.acs.org/email/cen/html090605064651.html
Very exciting news broadcast from CBS about a new breakthrough *drug treating the underlying cause* of Cystic Fibrosis.
http://humanbiology1010.blogspot.de/2011/11/cbs-news-video-o...
| Thank you for helping. |
| neutral |
Lirka
: yes, that's the idea behind it, but it sounds a bit forced in English...
1 hr
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|
Hi lirka, please see my discussion entry.
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| agree |
BrigitteHilgner
: curiosity killed the cat: there are more than one million and a half google hits for "treating the underlying cause" - I disagree with lirka's comment.
12 hrs
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Danke schön, Brigitte!
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Discussion
Examples:
If I apply a steroid ointment on an itching skin rash due to allergic reaction it will have a direct therapeutic effect (relieves itching and helps skin eruptions) but it will not treat the underlying cause (allergy to substance XYZ).
If I administer an analgesic in a patients with back pain due to bone metastases of prostate cancer, it will have a direct therapeutic effect (pain relief) but will not treat the underlying cause (metastases of prostate cancer).
If I prescribe ACE-inhibitors and diuretics in a patient with chronic heart failure due to ischemic cardiomypathy, it will have a direct therapeutic effect and hopefully improve left-ventricular failure but does not treat the underlying cause (cardiomyopathy).
Hemodialysis will have a direct therapeutic effect in a patient with stage 5 CRF (eliminating creatinine, urea and more) but will not treat the underlying cause (e.g. diabetic nephropathy, polycystic kidney disease...)