Glossary entry (derived from question below)
Spanish term or phrase:
placebo cargado
English translation:
spiked placebo
Added to glossary by
Rachel Freeman
Nov 3, 2012 17:20
11 yrs ago
5 viewers *
Spanish term
placebo cargado
Spanish to English
Other
Medical: Pharmaceuticals
Pharmaceutical trials
Hi everyone, this is taken from a Spanish pharmaceutical firm's report on the trials of a particular drug. The client wants UK English.
The section reads as follows:
EXACTITUD
Se ha evaluado la exactitud del método por medio del método del *placebo cargado.* Para ello se prepararon nueve muestras conteniendo placebo al 100% y diferentes cantidades de XXXXXX y YYYYY.
Accoridng to my research: Método del placebo cargado. Se prepara un placebo del problema que contiene todos los ingredientes excepto el analito a determinar, sobre dicho placebo se añaden cantidades conocidas de un analito patrón (estándar secundario) a tres niveles de concentración, dentro de rango a estudiar.
So I know what it is I just can't find what we would call it in English. Has anyone ever heard of this before? Thank you for your help!
The section reads as follows:
EXACTITUD
Se ha evaluado la exactitud del método por medio del método del *placebo cargado.* Para ello se prepararon nueve muestras conteniendo placebo al 100% y diferentes cantidades de XXXXXX y YYYYY.
Accoridng to my research: Método del placebo cargado. Se prepara un placebo del problema que contiene todos los ingredientes excepto el analito a determinar, sobre dicho placebo se añaden cantidades conocidas de un analito patrón (estándar secundario) a tres niveles de concentración, dentro de rango a estudiar.
So I know what it is I just can't find what we would call it in English. Has anyone ever heard of this before? Thank you for your help!
Proposed translations
(English)
4 +1 | spiked placebo | MedPharm |
4 +1 | loaded placebo | Neil Ashby |
Proposed translations
+1
1 hr
Selected
spiked placebo
An idea, given the context.
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Note added at 1 hr (2012-11-03 18:21:33 GMT)
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http://www.pharmaquality.com/ME2/Audiences/dirmod.asp?nm=&ty...
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Note added at 1 hr (2012-11-03 18:21:44 GMT)
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http://www.pharmaquality.com/ME2/Audiences/dirmod.asp?nm=&ty...
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Note added at 1 hr (2012-11-03 18:21:33 GMT)
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http://www.pharmaquality.com/ME2/Audiences/dirmod.asp?nm=&ty...
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Note added at 1 hr (2012-11-03 18:21:44 GMT)
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http://www.pharmaquality.com/ME2/Audiences/dirmod.asp?nm=&ty...
4 KudoZ points awarded for this answer.
Comment: "Thanks for your help!"
+1
1 hr
loaded placebo
As literal as that....
Gardasil presents elevated risks for sexually active women and ...
www.naturalnews.com/031098_Gardasil_risks.html
25 Jan 2011 – As previously reported, Merck's studies on Gardasil safety have been skewed from the outset due to using a "loaded" placebo. Instead of a ...
Asthma and Rhinitis - Volume 2 - Page 1824 - Google Books Result
books.google.co.uk/books?isbn=0470694815
William W. Busse, Stephen T. Holgate - 2008 - Medical
... with nasal congestion not attributed to allergies or 'cold' symptoms used either the spring-loaded external dilator at night or a nonspring-loaded placebo.
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Note added at 1 hr (2012-11-03 18:48:06 GMT)
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Placebos
healthrevelations.com/tag/placebos/
Since cancer patients are often lactose-intolerant, the drug and loaded “placebo” looked like they had similar side effects. But really, none of this is surprising.
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Note added at 22 hrs (2012-11-04 15:45:51 GMT)
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@ Joseph - There are three examples (i.e. not "neither" as you state in your comment). Admittedly, the SECOND example, "spring-loaded" is incorrect, but the other two are perfectly valid. It's simple - a "loaded-placebo" is a placebo that actually has active components in it, if not the primary active ingredient. In the question, a "placebo cargado" is placebo PLUS active ingredient at different concentrations. My examples are of "placebo" plus active ingredients, whether they are the principal active ingredient or not - they are "loaded placebos", i.e. they aren't just sugar.
Gardasil presents elevated risks for sexually active women and ...
www.naturalnews.com/031098_Gardasil_risks.html
25 Jan 2011 – As previously reported, Merck's studies on Gardasil safety have been skewed from the outset due to using a "loaded" placebo. Instead of a ...
Asthma and Rhinitis - Volume 2 - Page 1824 - Google Books Result
books.google.co.uk/books?isbn=0470694815
William W. Busse, Stephen T. Holgate - 2008 - Medical
... with nasal congestion not attributed to allergies or 'cold' symptoms used either the spring-loaded external dilator at night or a nonspring-loaded placebo.
--------------------------------------------------
Note added at 1 hr (2012-11-03 18:48:06 GMT)
--------------------------------------------------
Placebos
healthrevelations.com/tag/placebos/
Since cancer patients are often lactose-intolerant, the drug and loaded “placebo” looked like they had similar side effects. But really, none of this is surprising.
--------------------------------------------------
Note added at 22 hrs (2012-11-04 15:45:51 GMT)
--------------------------------------------------
@ Joseph - There are three examples (i.e. not "neither" as you state in your comment). Admittedly, the SECOND example, "spring-loaded" is incorrect, but the other two are perfectly valid. It's simple - a "loaded-placebo" is a placebo that actually has active components in it, if not the primary active ingredient. In the question, a "placebo cargado" is placebo PLUS active ingredient at different concentrations. My examples are of "placebo" plus active ingredients, whether they are the principal active ingredient or not - they are "loaded placebos", i.e. they aren't just sugar.
Peer comment(s):
neutral |
Joseph Tein
: Once we dismiss the "spring-loaded" nasal dilator - I questioned the technical correctness of "loaded" because of the quotation marks in the Merck reference. Also in your 3rd reference - I'm not convinced it shows that the term is widely used in research.
6 hrs
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"The first ref. relates to a non-inert placebo" - well what do you think the placebo in the question is??????????? A NON-INERT PLACEBO. The question discusses a 100% placebo PLUS "placebo cargado" with XXX and YYY. I assume XXX and YYY are non-intert!!!
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agree |
LEALZ
1 day 12 hrs
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