English to Spanish Medical Medical: Pharmaceuticals anticoagulantes

The elderly who may also have stroke and bleeding history, well, if they are on Warfarin, they may have fluctuating INRs - age has been mentioned already, and concomitant drugs. And that is a very important factor, not only for the medical patients, but also for the surgical patients, such as concomitant administration of anticoagulants, and **the end site**.

¿Podríais ayudarme? No entiendo el significado de esta última parte.