May 14, 2006 05:16
17 yrs ago
English term

first line

English to Malay Marketing Medical: Health Care
Is planned to receive first line chemotherapy for treatment of the metastatic breast cancer
Change log

May 14, 2006 06:11: Nasima Sarwar changed "Language pair" from "English" to "English to Malay"

Discussion

Sorry, I hadn't noticed that it is english-english this time. What is it exactly you want to know?

Proposed translations

+1
27 mins

initial treatment

HTH

A first line treatment or first line therapy is a medical therapy recommended for the initial treatment of a disease, sign or symptom, usually on the basis ...
en.wikipedia.org/wiki/First_line_treatment -





Peer comment(s):

neutral Michael Barnett : I think you have misunderstood the definition. A second line therapy would be used initially if the pt were allergic to the first line drug. If he were too young for the 2nd line drug, a 3rd line drug would be used initially.
7 mins
Well, the definition does say 'recommended'.
agree Alexander Demyanov : I think your understanding is absolutely correct. Plus, see, for example, http://lungcancercap.org/docstalk.htm
5 hrs
thanks, Alexander
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23 mins

treatment of (first) choice

http://en.wikipedia.org/wiki/First_line_treatment

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Note added at 26 mins (2006-05-14 05:43:20 GMT)
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Second or third line therapy may be used if, for example, the patient is allergic to the first line drug, or if it has failed for some reason.

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Note added at 10 hrs (2006-05-14 16:14:13 GMT)
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"First line therapy" is a term that is applied to a broad range of subjects in medicine, not just cancer therapy.

Penicillin, for instance, is first line therapy for "strep throat" because the microbe is virtually universally sensitive to this medication. However, patients who are known to be allergic to penicillin are given "second line" therapy, usually erythromycin. If the patient happens also to be allergic to erythromycin, he will be offered a "third line" treatment. Obviously, if the patient is known to be allergic beforehand, he is not going to be offered penicillin initially, unless, of course, the physician wishes to be sued for malpractice.

Similarly, first-line treatments are sometimes not prescribed initially because the drug may not be suitable for patients under 18 years of age, or perhaps there is a drug incompatibility with another medication that the patient is taking or perhaps the patient may simply not be able to afford the "first line" drug.

So, while the "first line" therapy is usually the initial treatment used, it can be seen from a careful reading of my reference that it is "first line" not becauase it is used initially, but because it has been determined from clinical trials to be the best therapy for a particular disorder.
Peer comment(s):

neutral Alexander Demyanov : The article you offer as a reference, doesn't talk about "2nd or 3rd line" used initially. Alternative therapy is used (alone or with the 1st ln th) if (i.e. AFTER it's determined that) the 1st line is failing or producing adverse side effects
5 hrs
Please see my note added at 10 hrs.
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8 days

pertama

Ayat ini terdapat di dalam internet: PADA mereka yang mengalami disfungsi ereksi, terapi pertama (first line therapy) yang harus ditawarkan adalah dengan obat-obatan yang diminum.
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200 days

barisan pertama

...to receive first line chemotherapy for treatment ..

.. untuk menerima kemoterapi barisan pertama sebagai rawatan ...

first line = first range of choice (of treatments)
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