располагающийся трансмембранно

English translation: transmembrane glycoprotein

15:17 Feb 16, 2010
Russian to English translations [PRO]
Medical - Biology (-tech,-chem,micro-) / HIV binding process
Russian term or phrase: располагающийся трансмембранно
This is in a description of how the HIV virus binds to a target cell. Here's a depiction of glycoprotein gp120 as the spiky things sticking out of the virion.
http://www.mcld.co.uk/hiv/?q=gp120
I think "трансмембранно" can be solved by turning it into an adjective and putting it with the gp120, since it's the gp120 which extends through the membrane (envelope) of the virion. But, then, does "располагающийся" emphasize that the spikes are "arranged" on the HIV envelope, or just that it has them?

"Деструкция клеток, несущих на своей поверхности рецепторы, способные сорбировать gp120, располагающийся трансмембранно у ВИЧ и способствующий связыванию его с клетками — мишенями."

Draft: "Destruction of cells which have surface receptors capable of sorbing the transmembrane glycoprotein gp120 of the HIV, which enables the virus bind to the target cells."

So, do I need to write "arranged on the HIV envelope" instead of merely "of the HIV," or something else? (Don't worry that it's not a full sentence; this is in a list of effects.)
Rachel Douglas
United States
Local time: 05:57
English translation:transmembrane glycoprotein
Explanation:
I'm not a virologist, but I guess the text and the link below will explain everything.
The glycoprotein gp120 is anchored to the viral membrane, or envelope, via non-covalent bonds with the transmembrane glycoprotein, gp41.


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Note added at 57 мин (2010-02-16 16:14:29 GMT)
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"of the HIV" will be enough, I guess
Selected response from:

Deep-one
Local time: 12:57
Grading comment
3 KudoZ points were awarded for this answer



Summary of answers provided
3 +1transmembrane glycoprotein
Deep-one


  

Answers


18 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
transmembrane glycoprotein


Explanation:
I'm not a virologist, but I guess the text and the link below will explain everything.
The glycoprotein gp120 is anchored to the viral membrane, or envelope, via non-covalent bonds with the transmembrane glycoprotein, gp41.


--------------------------------------------------
Note added at 57 мин (2010-02-16 16:14:29 GMT)
--------------------------------------------------

"of the HIV" will be enough, I guess


    Reference: http://en.wikipedia.org/wiki/Gp120
Deep-one
Local time: 12:57
Native speaker of: Native in RussianRussian
PRO pts in category: 3

Peer comments on this answer (and responses from the answerer)
agree  Judith Hehir: Looks right to me.
41 mins
  -> thanx
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