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09:54 Nov 6, 2015 |
French to English translations [PRO] Medical - Science (general) / pharmacodynamics | |||||||
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| Selected response from: Jonathan MacKerron | ||||||
Grading comment
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Summary of answers provided | ||||
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5 +2 | at the translation stage |
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2 +1 | expressed at the translational level |
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Summary of reference entries provided | |||
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translation |
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at the translation stage Explanation: Translational Control / Regulation of eIF4E and p70 S6K ... www.cellsignal.com/...translational.../translational.../p..... Traduire cette page Translation is a tightly regulated process, and the mTORC1-S6K signaling axis ... Ruvinsky I, Meyuhas O (2006) Ribosomal protein S6 phosphorylation: from ... |
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25 mins confidence: peer agreement (net): +1
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1 day 9 hrs |
Reference: translation Reference information: In molecular biology, "translation" is : "the process by which a particular sequence of bases in messenger RNA (mRNA) determines a sequence of amino acides in a polypeptide chain during protein and peptide biosynthesis". Source : Oxford Dictionary of Biochemistry and Molecular Biology, 2006, OUP, 2nd ed., p674. "the process by which the sequence of nucleotides in a messenger RNA moelcule directs the incorporation of amino acids into protein; occurs on a ribosome". Soucre : Essential Cell Biology, Alberts et al., 2010, Taylor & Francis, 3rd ed., G:22 (Glossary). (This is the "short" (>700 pages) edition of the classic work "Cell" by the same authors. Who better than Kaplan for the explanation? "Du RNA à la chaîne polypetidique: la traduction. Le RNA messager n'est qu'un intermédiaire entre le gène et la protéine. Il permet de résoudre le problème posé par le fait que chez les eucaryotes, les gènes et le système de traduction sont localisés dans deux compartiments différents. Mais là n'est pas le seul rôle du RNA Messenger (mRNA). En effet, la transcription permet la synthèse de nombreuses copies de mRNA à partir d'un seul gèn, chaque mRNA pouvant être traduit par plusieurs ribosomes. Il en résulte que, grâce au mRNA, la quantité de protéines synthétisées à partir de l'information d'un seul gène est considérablement amplifiée. Enfin, l'existence du mRNApermet d'introduire toute une série d'étapes de régulations possibles...". Source : Biologie moléculaire et médecine, 2007, Kaplan & Delpech, Flammarion, 3e éd., p104. -------------------------------------------------- Note added at 1 day9 hrs (2015-11-07 19:24:31 GMT) -------------------------------------------------- Sorry for the presentation. I should have separated them out more clearly. |
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