technique des "bouchons"
English translation: Cork gnawing test or cork gnawing method
| 07:51 Mar 1, 2020 |
| French to English translations [PRO] Medical - Medical: Pharmaceuticals / trial conducted on a medicinal product tested on animals | |||||||
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|  Selected response from: Magalie Modert Luxembourg Local time: 07:26 | ||||||
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| 3 +1 | Cork gnawing test or cork gnawing method |
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Answers
5 hrs confidence: 
peer agreement (net): +1
peer agreement (net): +1| technique des \"bouchons\" Cork gnawing test or cork gnawing method Explanation: I found a document that lists the different methods used for testing neuropharmaceuticals in rats and mice. On page 9+10 you can find the so called "cork gnawing test". I also found another paper were the cork gnawing method has been used to test an anxyolitic. The only thing I do not quite understand is why the cork gnawing test should be more influenced by the tonus than the two other tests, but maybe it depends on what specific drug or behaviour has been tested and possible adverse and side effects of the drug. I hope this helps. https://pdfs.semanticscholar.org/661b/791b9b9b350f59752c86e46b9764b67bd9db.pdf https://onlinelibrary.wiley.com/doi/abs/10.1002/ddr.430220208 |
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Reference comments
5 hrs |
| Reference Reference information: Maybe this can give you a further clue The hole-board test (HBT) is an experimental method used in scientific research to measure anxiety, stress, neophilia and emotionality in animals.[1][2][3] Because of its ability to measure multiple behaviors it is a popular test in behavioral pharmacology[ https://en.wikipedia.org/wiki/Hole-board_test Models of evaluation of pharmacological activity 1. Holeboard 2. RotaRod 3. Open field 4. Elevated Plus Maze 5. Dark-light box 6. Forced swimming test 7. Tail suspensión test http://bdigital.unal.edu.co/57175/7/NelsonH.HermidaGutiérrez... Bouchons: also stopper, blockage |
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