A privatif de grade 4

21:40 Dec 7, 2020
This question was closed without grading. Reason: No acceptable answer

French to English translations [PRO]
Medical - Medical (general) / haematological history
French term or phrase: A privatif de grade 4
Hi,

The patient suffers from an recurring angioimmunoblastic T-cell lymphoma.
She's been put on CHOEF, Bendamustine, Revlimid, Adcetris and finally Azacitidine
Here is the sentence
"report de la première cure par Azacitidine per os en raison d'une neutropénie A fébrile avec un A privatif de grade 4."

Thanks

Joanna
joanna menda
Canada
Local time: 00:36


Summary of answers provided
4Grade 4 Febrile neutropenia
Drmanu49
2grade 4 life-threatening
Stuart and Aida Nelson


Discussion entries: 3





  

Answers


1 hr   confidence: Answerer confidence 2/5Answerer confidence 2/5
grade 4 life-threatening


Explanation:

This is my educated guess as Phil would nicely say:

grade 4 life-threatening febrile neutropenia

http://www.bccancer.bc.ca/nursing-site/Documents/7. Fever an...

privatif, privative

Qui prive de quelque chose : Peine privative de liberté.

Qui indique la privation, l'absence (par exemple, le a de acéphale ou le in de insuccès).

https://www.larousse.fr/dictionnaires/francais/privatif/6400...

CTCAE Grade 4 Febrile neutropenia (fever of unknown origin without clinically or microbiologically documented infection)(ANC =38.5 degrees C)

https://www.ncbi.nlm.nih.gov/medgen/291738

Grade 4 Life-threatening or disabling AE

https://ctep.cancer.gov/protocoldevelopment/electronic_appli...

Azacitidine (Vidaza)

Increased risk of getting an infection is due to a drop in white blood cells.

Infections can sometimes be life threatening.

https://www.cancerresearchuk.org/about-cancer/cancer-in-gene...

Azacitidine Accord 25 mg/mL - Possible side effects


A fever. This could be due to an infection as a result of having low levels of white blood cells, which can be life-threatening.

https://www.medicines.org.uk/emc/files/pil.11088.pdf

Febrile neutropenia is the development of fever, often with other signs of infection, in a patient with neutropenia, an abnormally low number of neutrophil granulocytes (a type of white blood cell) in the blood.

https://en.wikipedia.org/wiki/Febrile_neutropenia

I wonder if A is a typo?

Stuart and Aida Nelson
United Kingdom
Local time: 05:36
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in SpanishSpanish
PRO pts in category: 28
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17 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
Grade 4 Febrile neutropenia


Explanation:
Prophylaxie de la Neutropénie Fébrile - AFSOS
www.afsos.org › Fiches referentiels
14 juil. 2014 — La neutropénie fébrile (NF) est associée à : Une morbidité et une mortalité importantes Un coût élevé pour la ... Le site de l'AFSOS propose des contenus pour le Grand Public et les Professionnels. ... fébrile. Fièvre + neutropénie de Grade 4 (ou neutropénie de Grade 3 avec grade 4 prévisible dans les 48h) ...

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Grade 4 Febrile Neutropenia, CTCAE (Concept Id: C1556691)
www.ncbi.nlm.nih.gov › medgen
Traduire cette page
Synonym: CTCAE Grade 4 Febrile neutropenia (fever of unknown origin without clinically or microbiologically documented infection)(ANC ...



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Note added at 17 heures (2020-12-08 14:46:23 GMT)
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Azacitidine Tablets for Continued Treatment in Acute Myeloid ...
ascopost.com › september-25-2020
Traduire cette page
25 sept. 2020 — The indications and dosing regimen for azacitidine tablets differ from ... common grade 3 or 4 adverse events included febrile neutropenia (11% ...

Effectiveness and safety of different azacitidine dosage ...
www.sciencedirect.com › article › pii
· Traduire cette page
Neutropenia was the most common grade 3–4 adverse event. These results suggest better effectiveness–tolerability profiles for 7-day schedules. Previous ...
de R García-Delgado · ‎2014

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Note added at 17 heures (2020-12-08 15:06:28 GMT)
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The first A could be for afébrile.
But I never heard of "A privatif de grade 4". Probably a typo.

(PDF) Consensus on diagnosis and empiric antibiotic therapy ...
www.researchgate.net › publication
· Traduire cette page
2 oct. 2020 — ... on the management of empiric therapy and diagnosis of febrile neutropenia (FN) were faced ... considered, while in high risk apyretic and no.

Drmanu49
France
Local time: 06:36
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in FrenchFrench
PRO pts in category: 5346
Notes to answerer
Asker: Thanks Dr Manu. But what I was stumped on was actually "A Privatif." Do you have any ideas?

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