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aurora

English translation: Aurora Protein Kinases

08:30 Oct 31, 2005
English language (monolingual) [PRO]
Medical - Genetics
English term or phrase: aurora
Genomic Organization, Expression, and Chromosome Localization of a Third Aurora-Related Kinase Gene, Aie1

£×hat does "aurora" mean here?

Thank you in advance!
envirostuden (X)
Selected answer:Aurora Protein Kinases
Explanation:
Abstract:

Aurora protein kinases are key players in different steps during mitosis and their activity is required for correct cell division. The inhibition of Aurora kinases is regarded as a promising approach for the development of novel anticancer agents. In the last few years several templates for ATP-competitive kinase inhibition have been successfully developed towards the inhibition of Aurora kinases, and the first compounds have recently entered clinical studies. This review summarises the patent literature up until March 2005 and the characteristics of the low molecular weight Aurora inhibitors described so far.

From: http://www.ingentaconnect.com/content/apl/etp/2005/00000015/...
Selected response from:

Dina Abdo
Palestine
Local time: 15:21
Grading comment
Thanks!
4 KudoZ points were awarded for this answer



SUMMARY OF ALL EXPLANATIONS PROVIDED
5 +9Aurora Protein Kinases
Dina Abdo


Discussion entries: 3





  

Answers


16 mins   confidence: Answerer confidence 5/5 peer agreement (net): +9
Aurora Protein Kinases


Explanation:
Abstract:

Aurora protein kinases are key players in different steps during mitosis and their activity is required for correct cell division. The inhibition of Aurora kinases is regarded as a promising approach for the development of novel anticancer agents. In the last few years several templates for ATP-competitive kinase inhibition have been successfully developed towards the inhibition of Aurora kinases, and the first compounds have recently entered clinical studies. This review summarises the patent literature up until March 2005 and the characteristics of the low molecular weight Aurora inhibitors described so far.

From: http://www.ingentaconnect.com/content/apl/etp/2005/00000015/...

Dina Abdo
Palestine
Local time: 15:21
Native speaker of: Native in ArabicArabic
PRO pts in category: 4
Grading comment
Thanks!

Peer comments on this answer (and responses from the answerer)
agree  Veronica Prpic Uhing: Professor D. Glover discovered and named the Polo and Aurora mitotic protein kinases
20 mins
  -> Thanks VPUHING :)
agree  Drunya: Aurora is the name of the gene
21 mins
  -> Thanks Drunya :)
agree  Vicky Papaprodromou: Good morning, Dina! :-)
56 mins
  -> Great morning Vicky, thank you :)
agree  Alfredo Tutino: Yes, just a name... :-)
1 hr
  -> Thanks Alfredo :)
agree  Romanian Translator (X)
2 hrs
  -> Thanks Awana :)
agree  PRAKASH SHARMA: :)
2 hrs
  -> Thanks Prakaash :)
agree  Camelia Frunză
5 hrs
  -> Thanks Camelia :)
agree  fareedeh ghassemi (X)
5 hrs
  -> Thanks Fareedeh :)
agree  Alfa Trans (X)
5 days
  -> Thanks Marju :)
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