vitamin k-dependent plasma glycoprotein

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00:54 May 17, 2020

English to Swedish translations [PRO]
COVID-19 - Science - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical (general), Journalism

English term or phrase: vitamin k-dependent plasma glycoprotein

Definition from Science Direct:
Vitamin K–dependent proteins, synthesized in the liver, play a central role in blood coagulation through either procoagulant or anticoagulant mechanisms. The vitamin K–dependent protein family includes the zymogen procoagulant factors VII, IX, X, and prothrombin, and the anticoagulants protein C, protein S, and protein Z

Example sentence(s):

This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. National Center for Biotechnology Info.
Protein Z is a vitamin K-dependent glycoprotein isolated and characterized from human and bovine plasma. A cDNA coding for human protein Z has been obtained by the isolation of phage clones from a liver cDNA library and in vitro amplification of two other liver libraries. Research Gate
Four proteins active in blood coagulation have long been known to require vitamin K for their proper biosynthesis: factors II, VII, IX, and X. This paper describes the purification of a hitherto unrecognized vitamin K-dependent glycoprotein from bovine plasma. The biosynthesis of this protein is interfered with by the vitamin K antagonist Dicoumarol. The JBC

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Summary of translations provided

vitamin K-beroende plasmaglykoprotein

Sven Petersson

Translations offered

6 hrs confidence:

vitamin K-beroende plasmaglykoprotein

Definition from own experience or research:
Ett plasmaglykoprotein om är beroende av vitamin K

Example sentence(s):

Protein C är ett vitamin K-beroende glykoprotein av blodplasma. Det syntetiseras av levern som ett inaktivt proenzym, som, under inverkan av trombin-trombomodulin-komplexet omvandlas till aktiv form. Aktiverat protein C - antikoagulant enzym selektivt inaktivera faktor Va och Villa genom deras hydrolys i närvaro av joniserat kalcium, fosfolipider och kofaktor - protein S, för att därigenom förhindra överföringen av protrombin till trombin. - ILive-portalen

Sven Petersson
Sweden
Local time: 22:21
Native speaker of:

Swedish,

English
PRO pts in category: 797

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