bioavailability

Serbian translation: biološka raspoloživost

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:bioavailability
Serbian translation:biološka raspoloživost

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16:59 Nov 17, 2009
English to Serbian translations [PRO]
Medical - Medical: Pharmaceuticals
Additional field(s): Medical: Cardiology, Medical (general)
English term or phrase: bioavailability
Definition from USC Kidney Transplant Program:
a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc.

Example sentence(s):
  • Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential. Merck & Co., Inc.
  • The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. Informa plc
  • Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. US National Institutes of Health
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biološka raspoloživost
Definition:
Nivo, mera u kojoj se određeni primenjeni lek absorbuje i uključuje u biološke procese u telu.
Selected response from:

Mira Stepanovic
Serbia
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
5 +2biološka raspoloživost
Mira Stepanovic
4bioraspoloživost
Katarina Delic


  

Translations offered


38 mins   confidence: Answerer confidence 5/5 peer agreement (net): +2
biološka raspoloživost


Definition from own experience or research:
Nivo, mera u kojoj se određeni primenjeni lek absorbuje i uključuje u biološke procese u telu.

Example sentence(s):
  • S i m p o z i j u m ‚‚Ispitivanje biološke raspoloživosti i biološke ekvivalentnosti lekova - regulatorni i praktični aspekti” - Agenc. za lekove i med. sredstva Srbije  
  • Sublingvalnom i rektalnom primenom postiže se bolja biološka raspoloživost, nego posle per os primene. - Farmaceutski fakultet, Beograd  
  • Koncentracije leka niže od očekivanih najčešće su rezultat slabe biološke raspoloživosti leka, njegove brže eliminacije u odnosu na očekivanu, povećanog volumena distribucije ili nepostignutog stanja ravnoteže (1,2,5). Alternativno praćenje imunosupresivnih - Medicinski fakultet, Niš  
Mira Stepanovic
Serbia
Local time: 09:23
Native speaker of: Native in SerbianSerbian, Native in Serbo-CroatSerbo-Croat
PRO pts in category: 72

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Milan Djukić
53 mins
  -> Hvala!

Yes  Natasa Djurovic
1 day 3 hrs
  -> Hvala!
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1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5
bioraspoloživost


Definition from Wikipedia:
U farmakologiji, bioraspoloživost se odnosi na udeo primenjene doze leka koji u neizmenjenom obliku dospeva u sistemsku cirkulaciju, i predstavlja jedan od osnovnih farmakokinetičkih parametara leka.

Example sentence(s):
  • Po definiciji, bioraspoloživost leka primenjenog intravenozno je 100%. - Wikipedia  
Katarina Delic
Local time: 09:23
Native speaker of: Native in SerbianSerbian
PRO pts in category: 17
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