housekeeping gene

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09:55 Apr 20, 2010
English to Hebrew translations [PRO]
Medical - Genetics
Additional field(s): Biology (-tech,-chem,micro-)
English term or phrase: housekeeping gene
Definition from Wikipedia:
A housekeeping gene is typically a constitutive gene that is required for the maintenance of basal cellular function, and are found in all human cells.[1][2] Although some housekeeping genes are expressed at relatively constant levels(such as HSP90 and Beta-actin), other housekeeping genes may vary depending on experimental conditions.

Example sentence(s):
  • Here, the non-regulation of seven housekeeping genes (beta-tubulin, cyclophilin, actin, elongation factor 1-alpha (ef1alpha), 18S rRNA, adenine phosphoribosyl transferase (aprt), and cytoplasmic ribosomal protein L2) during biotic (late blight) and abiotic stresses (cold and salt stress) was tested on potato plants using geNorm software. National Center for Biotechnology Inform
  • An inherent assumption in the use of housekeeping genes is that expression of the genes remains constant in the cells or tissues under investigation. Although exceptions to this assumption are well documented, housekeeping genes are of value in fully characterized systems. American Physiological Society
  • The researchers propose that many other housekeeping genes in addition to HPRT may also be found to regulate important developmental pathways. MediLexicon International Ltd
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Summary of translations provided
5 +1גן של תחזוקה שוטפת
Odded Leon


  

Translations offered


7 days   confidence: Answerer confidence 5/5 peer agreement (net): +1
גן של תחזוקה שוטפת


Definition from own experience or research:
גן של תחזוקה שוטפת הינו גן המתבטא באופן רציף ובכמות קבועה בכל תאי הגוף או כמעט בכולם. תוצרי הגנים של תחזוקה שוטפת הם בדרך כלל חלבונים הנדרשים באופן רציף לתפקודו הבסיסי של התא. ולכן, במרבית תנאי הניסוי, יוצאים מתוך הנחה שרמת הביטוי של הגנים לתחזוקה שוטפת אינה משתנה.

Example sentence(s):
  • חלק מהגנים מתבטאים בכל התאים ברציפות ונקראים גנים של תחזוקה שוטפת, כגון תוצרי גנים האחראים לתהליך נשימה תאית. - אוניברסיטת בר אילן  
Odded Leon
Israel
Local time: 14:14
Native speaker of: Hebrew

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Tzviya Levin Rifkind
2 days 14 hrs
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