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  3. Genetics

biliary cell/s

German translation: Gallenzelle

18:12 Aug 3, 2011
English to German translations [PRO]
Medical - Genetics / stem cell
English term or phrase: biliary cell/s
Context:

methods to isolate and culture cells that have many features essential to hepatic progenitors, including expression of specific markers and the potential to differentiate into either hepatocytes or biliary cells.
Gabriella Bertelmann
Local time: 01:39
German translation:Gallenzelle
Explanation:
Selected response from:

Alexander Ryshow
Belarus
Local time: 02:39
Grading comment
thank you
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +3Cholangiozyt(en)
Marga Shaw
3Gallenzelle
Alexander Ryshow
2 +1Gallengangszellen
liz askew
Summary of reference entries provided
liz askew

  

Answers


4 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
Gallenzelle


Explanation:


Alexander Ryshow
Belarus
Local time: 02:39
Native speaker of: Native in RussianRussian
PRO pts in category: 4
Grading comment
thank you
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19 mins   confidence: Answerer confidence 2/5Answerer confidence 2/5 peer agreement (net): +1
Gallengangszellen


Explanation:
based on the findings only

liz askew
United Kingdom
Local time: 00:39
Native speaker of: Native in EnglishEnglish

Peer comments on this answer (and responses from the answerer)
agree  Anne Schulz
14 hrs
  -> Thank you Anne!
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5 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +3
Cholangiozyt(en)


Explanation:
EN:
Notch-mediated biliary expansion involved proliferation of existing ducts or the recruitment of new biliary cells (cholangiocytes) is not known.
http://dev.biologists.org/content/131/22/5753.full

DE:
Zu Beginn befinden sich in der Leber Hepatoblasten, die als Vorläuferzellen für Hepatozyten und Cholangiozyten
fungieren.
http://docserv.uni-duesseldorf.de/servlets/DerivateServlet/D...

Ruhende hepatische Stammzellen werden nach bestimmten Reizen aktiviert, sie proliferieren und können zu Hepatozyten oder Cholangiozyten ausdifferenzieren. http://www.google.com/search?q=Stammzellen Hepatozyten Chola...

Neben dem regenerativen Potential der Hepatozyten stellen Ovalzellen eine Quelle für bi-potenzielle Progenitorzellen dar, die die Fähigkeit zur Differenzierung in Hepatozyten und Gallengangsepithelzellen (Cholangiozyten) besitzen [3-5].
http://www.aco-asso.at/manual/aktuell/Hepatozellulaeres-karz...



Marga Shaw
United Kingdom
Local time: 00:39
Specializes in field
Native speaker of: German
PRO pts in category: 36

Peer comments on this answer (and responses from the answerer)
agree  Harald Moelzer (medical-translator)
6 hrs
  -> Danke, Harald!
agree  Konrad Schultz: alle Identitäten in Einem: http://www.aerzteblatt.de/v4/archiv/artikel.asp
8 hrs
  -> Dank, Konrad, auch für den zusätzlichen Link!
agree  Anne Schulz
9 hrs
  -> Dank, Anne!
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Reference comments


12 mins
Reference

Reference information:
[PDF]
Diagnostik der Cholangiopathien
- [ Translate this page ]
data.aerzteblatt.org/pdf/100/45/a2955.pdf
File Format: PDF/Adobe Acrobat
den Gallengangsepithelien (Cholan- giozyten). Letztere sind polarisiert ... Biliary epithelial cells (cholangiocytes) which ... zellen zu sein, die auf bestimmte Stimuli mit DNA/RNA-Synthese reagieren, um dann zu differenzierten Zellen ...

--------------------------------------------------
Note added at 18 mins (2011-08-03 18:31:19 GMT)
--------------------------------------------------

http://webdoc.sub.gwdg.de/diss/2005/cimica/

Under certain circumstances like in hepatocarcinogenesis and chronic liver injury caused by drugs, viruses and toxins, when the hepatocytes proliferation is impaired, facultative hepatic stem cells called “oval cells” are recruited to generate the hepatic lineages of the hepatocytes and *** biliary cells***. Hence, it was proposed that oval cells could represent a second compartment involved in the liver regeneration when the insult of the organ is too massive and proliferation of hepatocytes is suppressed.
Unter bestimmten Umständen wie z.B. Hepatokarzinogenese oder einer durch Drogen, Viren oder Toxine induzierten chronischen Leberschädigung, wenn die proliferative Fähigkeit der Hepatozyten beeinträchtigt ist, kommt es zur Rekrutierung fakultativer hepatischer Stammzellen den so genannten „Ovalzellen“ die in der Lage sind Hepatozyten und ****Gallengangszellen ***zu generieren. Es kann daher angenommen werden, dass die Ovalzellen ein zweites Kompartiment sind, dass an der Regeneration der Leber beteiligt ist, wenn diese massiv geschädigt und die Proliferation der Hepatozyten suprimiert ist.

liz askew
United Kingdom
Native speaker of: Native in EnglishEnglish
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