13:17 Jul 10, 2020
Der Titel lautet "METHOD TO DIAGNOSE INFECTIOUS PERITONITIS AND PREDICT THE SEVERITY AND OUTCOME THEREOF IN HUMANS."
und hier mehrere Sätze vor und nah dem Satz mit "Diversion": In patients with polytrauma and infection, PSP/reg levels were further increased. Finally, polytraumatic patients exhibiting sepsis showed a large increase in serum PSP/reg. The appearance of PSP/reg in blood serum would imply an altered pathway, diverting the protein from pancreatic juice into the blood. It has also been shown that members of the lectin binding family (e.g. pancreatitis-associated protein) are inducible by cytokines. There is a strong and concerted action of cytokines after trauma. The complexity of the cytokine response, with many different cytokines being released, is not understood. Thus it is likely that PSP/reg reacts to cytokines that are raised under condition of systemic stress or trauma. In contrast, other pancreatic enzymes, e.g. amylase and lipase, appear not to be regulated by cytokines, their appearance in the blood being a result of diversion only. The PSP/reg level in blood serum was recently proven to be a reliable indicator of systemic sepsis. Now PSP/reg levels in blood |