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  3. Medical: Pharmaceuticals

sham

French translation: faussement traité ou par injection simulée

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:sham
French translation:faussement traité ou par injection simulée
Entered by: Drmanu49

13:09 May 11, 2020
English to French translations [PRO]
COVID-19 - Medical - Medical: Pharmaceuticals / tests de vaccins anti-coronavirus
English term or phrase: sham
Subsequently, we conducted a challenge study by a direct inoculation of 106 TCID50 of SARS-CoV-2 CN1 into the animal lung through the intratracheal route at day 22 (one week after the third immunization) in vaccinated and control macaques to verify the protective efficacy. Expectedly, all control (sham and placebo) macaques showed excessive copies (104-106/ml) of viral genomic RNA in the pharynx, crissum and lung by day 3-7 post-inoculation (dpi) and severe interstitial pneumonia
orgogozo
France
Local time: 15:51
faussement traité ou par injection simulée
Explanation:
Placebo and sham treatment are methods used in medical trials to help researchers determine the effectiveness of a drug or treatment. Placebos are inactive substances used to compare results with active substances. And in sham treatments, the doctor goes through the motions without actually performing the treatment.

A placebo is often used in a drug trial to help show whether the drug being studied is more effective than an inactive "sugar pill." Some of the people in the drug trial get the active drug while others get the inactive placebo. The results of each group are compared.

In a sham treatment, some people get the real treatment while others get the sham treatment. Then the results are compared.

Essais cliniques - Orphanet
www.orpha.net › cgi-bin › ResearchTrials_ClinicalTrials
REVERSE: Etude clinique pivotale randomisée, en double aveugle, contrôlée par injection simulée (SHAM), évaluant l'efficacité d'une injection intravitréenne ...
Selected response from:

Drmanu49
France
Local time: 15:51
Grading comment
merci à tous
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +3faussement traité ou par injection simulée
Drmanu49
4 +1simulé
Diana Donzelli-Gaudet
4simulé/factice
Rocsana Guignaudeau
4en aveugle (en insu)
Marcombes (X)


  

Answers


4 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
simulé


Explanation:
... tous les contrôles (simulés ou placébo)...

Diana Donzelli-Gaudet
Local time: 15:51
Specializes in field
Native speaker of: Native in ItalianItalian, Native in FrenchFrench

Peer comments on this answer (and responses from the answerer)
agree  Susanne Toito
2 hrs
  -> Merci Susanne !
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6 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
faussement traité ou par injection simulée


Explanation:
Placebo and sham treatment are methods used in medical trials to help researchers determine the effectiveness of a drug or treatment. Placebos are inactive substances used to compare results with active substances. And in sham treatments, the doctor goes through the motions without actually performing the treatment.

A placebo is often used in a drug trial to help show whether the drug being studied is more effective than an inactive "sugar pill." Some of the people in the drug trial get the active drug while others get the inactive placebo. The results of each group are compared.

In a sham treatment, some people get the real treatment while others get the sham treatment. Then the results are compared.

Essais cliniques - Orphanet
www.orpha.net › cgi-bin › ResearchTrials_ClinicalTrials
REVERSE: Etude clinique pivotale randomisée, en double aveugle, contrôlée par injection simulée (SHAM), évaluant l'efficacité d'une injection intravitréenne ...

Drmanu49
France
Local time: 15:51
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in FrenchFrench
PRO pts in category: 1923
Grading comment
merci à tous

Peer comments on this answer (and responses from the answerer)
agree  Samuel Clarisse
2 hrs
  -> Thank you.
agree  Daryo: you can hear real experience talking ...
6 hrs
  -> Thank you.
agree  Christine HOUDY: D'accord
7 hrs
  -> Thank you.
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2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
simulé/factice


Explanation:
J'ai trouvé un texte provenant du site www.radiopharm.ca où le mot "sham" est traduit par "simulé" (à voir les exemples de ce formulaire)



Example sentence(s):
  • An analysis of three rigorous studies found that TENS was no better than placebo or sham TENS for chronic low back pain.
  • L'analyse de trois études rigoureuses a révélé que, pour soulager la lombalgie chronique, la TENS n'était pas plus efficace que le placebo ou la TENS simulée.
Rocsana Guignaudeau
France
Local time: 15:51
Native speaker of: Native in RomanianRomanian
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3 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
en aveugle (en insu)


Explanation:
en aveugle et placébo

--------------------------------------------------
Note added at 3 heures (2020-05-11 17:02:43 GMT)
--------------------------------------------------

Le placebo est une présentation à l’identique du médicament à l’étude mais qui ne contient pas le principe actif. Ainsi lorsqu’un essai randomisé contre placebo est réalisé, un sujet dans l’essai recevra au hasard soit le médicament à l’étude soit une copie de ce médicament, et ni ce sujet, ni le médecin qui le prend en charge dans l’étude, ni la personne (souvent le médecin) qui évaluera le critère de jugement ne sauront ce qui est réellement pris. On parle dans ce cas de mise en insu ou d’aveugle. Les sujets recevant le placebo constituent ce que l’on appelle le groupe témoin (ou groupe contrôle par anglicisme).


    Reference: http://www.minerva-ebm.be/fr/article/182
Marcombes (X)
France
Local time: 15:51
Native speaker of: Native in FrenchFrench
PRO pts in category: 12
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