English to French Medical Medical: Pharmaceuticals Heart failure

Reduces the severity and frequency of heart failure symptoms in chronic HF patients but no improvement in day-to-day activities according to patient reported outcomes
Asymptomatic troponin levels similar to placebo
Slight increase in high sensitive troponin levels but not related to symptoms of ischemic events
***Pk base dose adjustment*** at point-of-care with one office visit
***Pk base dose adjustment*** and one drug plasma level assessment, requiring multiple (two or three) office visits
Statistically significant data on reverse remodeling in 9 months