Glossary entry

English term or phrase:

co-primary outcome variables

Greek translation:

δεύτερες κύριες μεταβλητές έκβασης

Added to glossary by Katerina Athanasaki
Apr 3, 2006 11:54
18 yrs ago
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English term

co-primary outcome variables

English to Greek Medical Medical (general) clinical study
"Study XXX (όνομα μελέτης) showed statistically significant and consistent efficacy of XXX (όνομα δραστικής ουσίας) during both Period 1 and Period 2 on the primary and *co-primary outcome variables* using the predefined response definition (75% rule)."
Η ερώτησή μου εδώ είναι: μπορώ το co-primary να το πω "δευτερεύουσες"; Υποθέτω ότι αποκαλεί τις μεταβλητές "co-primary" γιατί δεν θέλει να τις υποβιβάσει σε δευτερεύουσες. Κάτι σε "συνκύριες" (sic) ή "συμπρωταρχικές" (sic) θέλει να τις πει αλλά δε μπορώ να σκεφτώ κάτι δόκιμο.

Discussion

Effie Emmanouilidou Apr 3, 2006:
Den ksero pos mporeis na to peis : (, alla exo vrei "primary, coprimary, and secondary", opote einai kati diaforetiko. Isos "συμπρωτεύουσες(simproteuouses)", an kai thimizei tis poleis?

Proposed translations

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δεύτερες κύριες μεταβλητές έκβασης

Έχω σε γλωσσάρι μου co-primary endpoints - δεύτερα κύρια τελικά σημεία. Δεν θυμάμαι που το βρήκα τότε, αλλά αν μπορείς να περιμένεις μέχρι το βραδάκι θα σου πω :)

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Note added at 22 hrs (2006-04-04 10:08:24 GMT)
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Τελικά έψαξα και ο όρος στο γλωσσάρι μου προέρχεται από γλωσσάρι πελάτη για "coprimary end points" (=δεύτερα κύρια τελικά σημεία).

Εδώ βρήκα μερικούς ορισμούς στα Αγγλικά, μήπως βγει άκρη:

http://www.findarticles.com/p/articles/mi_qa3899/is_199810/a...

Definition 1. A clinical endpoint is a clinical variable which either directly or indirectly reflects the condition of an underlying disease.

Definition 2. A clinical endpoint is a primary endpoint if it satisfies the following conditions:

It provides a measure of clinical benefit realized in the patient that is acceptable by the clinician as a meaningful measure of the drug effect for the disease under treatment, and

It is an endpoint such that a positive finding in this endpoint alone is sufficient to result in the claim, regardless of what other endpoints show.

Comment: Primary endpoints are rare and must be well established in their relationship to the disease, the treatment, and the quality and objectivity of the endpoint. A good example of a primary endpoint is mortality, say, in a congestive heart failure trial.

Definition 3. A clinical endpoint is a coprimary endpoint if it satisfies the following conditions:

It provides a measure of clinical benefit realized in the patient that is acceptable by the clinician as a meaningful measure of the drug effect for the disease under treatment, and

It is an endpoint such that a positive finding in this endpoint alone is sufficient to result in the claim, provided any primary endpoint(s), or some equally important coprimary endpoints are not showing a negative effect.

Definition 4. A clinical endpoint is called secondary if it satisfies the following conditions:

It provides a measure of clinical benefit realized in the patient that is acceptable by the clinician as a meaningful measure of the drug effect for the disease under treatment, and

It is an endpoint such that a positive finding in this endpoint alone is not sufficient to result in the claim.

Comment: A secondary endpoint together with other secondary endpoints, however, may provide sufficient evidence to result in a claim. It may provide supportive evidence to the primary or coprimary endpoints.


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4 KudoZ points awarded for this answer. Comment: "Σ΄ευχαριστώ πολύ Κωνσταντίνα!"
1 day 5 hrs

συγκύριες μεταβλητές έκβασης

Θα πρότεινα κάτι τέτοιο γιατί ο όρος primary μεταφράζεται
κύριες, πρωτεύουσες
έναντι της δευτερεύουσας μεταβλητής (secondary)
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